Core Laboratories
Laser Microdissection Core

Director: Norman Lewis

Contact: 335-2682

Summary
Cell and tissue-specific analysis of genes, proteins and the metabolome is becoming increasingly important in order to elucidate physiological function. Several techniques such as immunolocalization, in situ hybridization and reporter gene visualization have been previously used for such purposes with differing levels of success. Laser capture microdissection (LCM) is a relatively new technique which makes it possible now to excise and harvest individual cells from tissue sections. Such harvested cells can provide DNAs, RNAs, proteins and metabolites for a plethora of applications including gene expression profiling, as well as proteomic and metabolite analyses of individual cell and tissue types.

Resources

PALM MicroBeam Laser Dissection Core – Laser micromanipulation system for microdissection with UV-A laser

Services:

Provide technical support for microdissection of target tissues and cells from tissue sections